Los Angeles Chargers vs San Francisco 49ers Odds, Top Picks & Predictions

San Francisco 49ers

Los Angeles Chargers

Upcoming Thursday, Dec 17

Kickoff: 8:15 PM

SoFi Stadium, Inglewood

Match Facts

League: National Football League
Week: Week 15
Date: 12/17/2026
Venue: SoFi Stadium

Los Angeles hosts San Francisco in Week 15 on December 17 at SoFi Stadium in Inglewood. The Chargers went 11-6 last season. The 49ers went 12-5. No prior meeting on record.

Last season the 49ers outscored the Chargers 437-368, and LA’s defense brought 50 sacks to San Francisco’s 23.

Week 15 at SoFi Stadium

The Chargers host the 49ers in Week 15. Kickoff is December 17 at SoFi Stadium in Inglewood. LA is the home side. San Francisco travels south to open their first-ever meeting.

Season form

Los Angeles finished last season at 11-6, second in the AFC West. Their last five: L-L-L-W-W. San Francisco went 12-5, third in the NFC West. Their last five: L-W-L-W-W.

Offense vs defense

San Francisco’s 437 points beat LA’s 368. The 49ers threw for 4,571 yards and 36 passing touchdowns. The Chargers countered with 50 sacks and 20 interceptions. San Francisco managed 23 sacks and 6 picks.

Head-to-head history

These teams have never met. No prior meeting on record. Week 15 at SoFi Stadium is the first. Expect the record book to get its first entry.

When do the Chargers and 49ers play?

Week 15, December 17, 2026. Kickoff at SoFi Stadium in Inglewood.

What was the Chargers’ record last season?

11-6, second in the AFC West. They scored 368 points and allowed 340.

What was the 49ers’ record last season?

12-5, third in the NFC West. They scored 437 points and allowed 371.

Have these teams met before?

No. No prior meeting on record. Week 15 is the first.

Which divisions do the Chargers and 49ers play in?

Chargers in the AFC West. 49ers in the NFC West.

Next Match

Week 15 · SoFi Stadium · San Francisco 49ers vs Los Angeles Chargers

Regular Season NFL match-ups by week 272 games ▾

▼ Week 1 16 games

Thu, Sep 10

San Francisco 49ers at Los Angeles Rams, Week 1

8:35 PM · SoFi Stadium · Netflix

Sun, Sep 13

Chicago Bears at Carolina Panthers, Week 1

1:00 PM · Bank Of America Stadium · Fox

Sun, Sep 13

Tampa Bay Buccaneers at Cincinnati Bengals, Week 1

1:00 PM · Paycor Stadium · Fox

Sun, Sep 13

New Orleans Saints at Detroit Lions, Week 1

1:00 PM · Ford Field · Fox

Sun, Sep 13

Buffalo Bills at Houston Texans, Week 1

1:00 PM · NRG Stadium · CBS

Sun, Sep 13

Baltimore Ravens at Indianapolis Colts, Week 1

1:00 PM · Lucas Oil Stadium · CBS

Sun, Sep 13

Cleveland Browns at Jacksonville Jaguars, Week 1

1:00 PM · EverBank Stadium · CBS

Sun, Sep 13

Miami Dolphins at Las Vegas Raiders, Week 1

4:25 PM · Allegiant Stadium · Fox

Sun, Sep 13

Arizona Cardinals at Los Angeles Chargers, Week 1

4:25 PM · SoFi Stadium · CBS

Sun, Sep 13

Green Bay Packers at Minnesota Vikings, Week 1

4:25 PM · U.S. Bank Stadium · CBS

Sun, Sep 13

Dallas Cowboys at New York Giants, Week 1

8:20 PM · MetLife Stadium · NBC

Sun, Sep 13

Washington Commanders at Philadelphia Eagles, Week 1

4:25 PM · Lincoln Financial Field · Fox

Sun, Sep 13

Atlanta Falcons at Pittsburgh Steelers, Week 1

1:00 PM · Acrisure Stadium · Fox

Sun, Sep 13

New York Jets at Tennessee Titans, Week 1

1:00 PM · Nissan Stadium · CBS

Mon, Sep 14

Denver Broncos at Kansas City Chiefs, Week 1

8:15 PM · Arrowhead Stadium · ESPN

Wed, Sep 9

New England Patriots at Seattle Seahawks, Week 1

8:20 PM · Lumen Field · NBC

▼ Week 2 16 games

Thu, Sep 17

Detroit Lions at Buffalo Bills, Week 2

8:15 PM · Highmark Stadium · Prime Video

Sun, Sep 20

Seattle Seahawks at Arizona Cardinals, Week 2

4:25 PM · State Farm Stadium · Fox

Sun, Sep 20

Carolina Panthers at Atlanta Falcons, Week 2

1:00 PM · Mercedes Benz Stadium · Fox

Sun, Sep 20

New Orleans Saints at Baltimore Ravens, Week 2

1:00 PM · M And T Bank Stadium · CBS

Sun, Sep 20

Minnesota Vikings at Chicago Bears, Week 2

1:00 PM · Soldier Field · Fox

Sun, Sep 20

Washington Commanders at Dallas Cowboys, Week 2

4:25 PM · At And T Stadium · Fox

Sun, Sep 20

Jacksonville Jaguars at Denver Broncos, Week 2

4:05 PM · Empower Field at Mile High · CBS

Sun, Sep 20

Cincinnati Bengals at Houston Texans, Week 2

1:00 PM · NRG Stadium · CBS

Sun, Sep 20

Indianapolis Colts at Kansas City Chiefs, Week 2

8:20 PM · Arrowhead Stadium · NBC

Sun, Sep 20

Las Vegas Raiders at Los Angeles Chargers, Week 2

4:05 PM · SoFi Stadium · CBS

Sun, Sep 20

San Francisco 49ers at Miami Dolphins, Week 2

4:25 PM · Hard Rock Stadium · Fox

Sun, Sep 20

Pittsburgh Steelers at New England Patriots, Week 2

1:00 PM · Gillette Stadium · CBS

Sun, Sep 20

Green Bay Packers at New York Jets, Week 2

1:00 PM · MetLife Stadium · Fox

Sun, Sep 20

Tennessee Titans at Philadelphia Eagles, Week 2

1:00 PM · Lincoln Financial Field · Fox

Sun, Sep 20

Cleveland Browns at Tampa Bay Buccaneers, Week 2

1:00 PM · Raymond James Stadium · CBS

Mon, Sep 21

New York Giants at Los Angeles Rams, Week 2

8:15 PM · SoFi Stadium · ESPN / ESPN/ABC

▼ Week 3 16 games

Thu, Sep 24

Atlanta Falcons at Green Bay Packers, Week 3

8:15 PM · Lambeau Field · Prime Video

Sun, Sep 27

Los Angeles Chargers at Buffalo Bills, Week 3

1:00 PM · Highmark Stadium · Fox

Sun, Sep 27

Pittsburgh Steelers at Cincinnati Bengals, Week 3

1:00 PM · Paycor Stadium · CBS

Sun, Sep 27

Carolina Panthers at Cleveland Browns, Week 3

1:00 PM · Huntington Bank Field · Fox

Sun, Sep 27

Baltimore Ravens at Dallas Cowboys, Week 3

4:25 PM · At And T Stadium · CBS

Sun, Sep 27

Los Angeles Rams at Denver Broncos, Week 3

8:20 PM · Empower Field at Mile High · NBC

Sun, Sep 27

New York Jets at Detroit Lions, Week 3

1:00 PM · Ford Field · Fox

Sun, Sep 27

Houston Texans at Indianapolis Colts, Week 3

1:00 PM · Lucas Oil Stadium · CBS

Sun, Sep 27

New England Patriots at Jacksonville Jaguars, Week 3

1:00 PM · EverBank Stadium · CBS

Sun, Sep 27

Kansas City Chiefs at Miami Dolphins, Week 3

1:00 PM · Hard Rock Stadium · CBS

Sun, Sep 27

Las Vegas Raiders at New Orleans Saints, Week 3

4:25 PM · Caesars Superdome · CBS

Sun, Sep 27

Tennessee Titans at New York Giants, Week 3

1:00 PM · MetLife Stadium · CBS

Sun, Sep 27

Arizona Cardinals at San Francisco 49ers, Week 3

4:05 PM · Levis Stadium · Fox

Sun, Sep 27

Minnesota Vikings at Tampa Bay Buccaneers, Week 3

4:05 PM · Raymond James Stadium · Fox

Sun, Sep 27

Seattle Seahawks at Washington Commanders, Week 3

1:00 PM · Northwest Stadium · Fox

Mon, Sep 28

Philadelphia Eagles at Chicago Bears, Week 3

8:15 PM · Soldier Field · ESPN

▼ Week 4 16 games

Thu, Oct 1

Pittsburgh Steelers at Cleveland Browns, Week 4

8:15 PM · Huntington Bank Field · Amazon Prime / Prime Video

Sun, Oct 4

Tennessee Titans at Baltimore Ravens, Week 4

1:00 PM · M And T Bank Stadium · CBS

Sun, Oct 4

New England Patriots at Buffalo Bills, Week 4

1:00 PM · Highmark Stadium · CBS

Sun, Oct 4

Detroit Lions at Carolina Panthers, Week 4

8:20 PM · Bank Of America Stadium · NBC

Sun, Oct 4

New York Jets at Chicago Bears, Week 4

1:00 PM · Soldier Field · Fox

Sun, Oct 4

Jacksonville Jaguars at Cincinnati Bengals, Week 4

1:00 PM · Paycor Stadium · CBS

Sun, Oct 4

Houston Texans at Dallas Cowboys, Week 4

1:00 PM · At And T Stadium · Fox

Sun, Oct 4

Tampa Bay Buccaneers at Green Bay Packers, Week 4

1:00 PM · Lambeau Field · Fox

Sun, Oct 4

Kansas City Chiefs at Las Vegas Raiders, Week 4

4:25 PM · Allegiant Stadium · CBS

Sun, Oct 4

Miami Dolphins at Minnesota Vikings, Week 4

4:05 PM · U.S. Bank Stadium · Fox

Sun, Oct 4

Arizona Cardinals at New York Giants, Week 4

1:00 PM · MetLife Stadium · CBS

Sun, Oct 4

Los Angeles Rams at Philadelphia Eagles, Week 4

1:00 PM · Lincoln Financial Field · Fox

Sun, Oct 4

Denver Broncos at San Francisco 49ers, Week 4

4:25 PM · Levis Stadium · CBS

Sun, Oct 4

Los Angeles Chargers at Seattle Seahawks, Week 4

4:25 PM · Lumen Field · CBS

Sun, Oct 4

Indianapolis Colts at Washington Commanders, Week 4

9:30 AM · Northwest Stadium · NFL Network

Mon, Oct 5

Atlanta Falcons at New Orleans Saints, Week 4

8:15 PM · Caesars Superdome · ESPN

▼ Week 5 15 games

Thu, Oct 8

Tampa Bay Buccaneers at Dallas Cowboys, Week 5

8:15 PM · At And T Stadium · Prime Video

Sun, Oct 11

Detroit Lions at Arizona Cardinals, Week 5

4:25 PM · State Farm Stadium · Fox

Sun, Oct 11

Baltimore Ravens at Atlanta Falcons, Week 5

8:20 PM · Mercedes Benz Stadium · NBC

Sun, Oct 11

Los Angeles Chargers at Denver Broncos, Week 5

4:05 PM · Empower Field at Mile High · CBS

Sun, Oct 11

Chicago Bears at Green Bay Packers, Week 5

4:25 PM · Lambeau Field · Fox

Sun, Oct 11

Tennessee Titans at Houston Texans, Week 5

1:00 PM · NRG Stadium · CBS

Sun, Oct 11

Pittsburgh Steelers at Indianapolis Colts, Week 5

1:00 PM · Lucas Oil Stadium · CBS

Sun, Oct 11

Philadelphia Eagles at Jacksonville Jaguars, Week 5

9:30 AM · EverBank Stadium · NFL Network

Sun, Oct 11

Cincinnati Bengals at Miami Dolphins, Week 5

1:00 PM · Hard Rock Stadium · Fox

Sun, Oct 11

New Orleans Saints at Minnesota Vikings, Week 5

1:00 PM · U.S. Bank Stadium · Fox

Sun, Oct 11

Las Vegas Raiders at New England Patriots, Week 5

1:00 PM · Gillette Stadium · CBS

Sun, Oct 11

Cleveland Browns at New York Jets, Week 5

1:00 PM · MetLife Stadium · CBS

Sun, Oct 11

San Francisco 49ers at Seattle Seahawks, Week 5

4:25 PM · Lumen Field · Fox

Sun, Oct 11

New York Giants at Washington Commanders, Week 5

1:00 PM · Northwest Stadium · Fox

Mon, Oct 12

Buffalo Bills at Los Angeles Rams, Week 5

8:15 PM · SoFi Stadium · ESPN

▼ Week 6 14 games

Thu, Oct 15

Seattle Seahawks at Denver Broncos, Week 6

8:15 PM · Empower Field at Mile High · Prime Video

Sun, Oct 18

Chicago Bears at Atlanta Falcons, Week 6

1:00 PM · Mercedes Benz Stadium · Fox

Sun, Oct 18

Baltimore Ravens at Cleveland Browns, Week 6

1:00 PM · Huntington Bank Field · Fox

Sun, Oct 18

Dallas Cowboys at Green Bay Packers, Week 6

8:20 PM · Lambeau Field · NBC

Sun, Oct 18

Tennessee Titans at Indianapolis Colts, Week 6

1:00 PM · Lucas Oil Stadium · Fox

Sun, Oct 18

Houston Texans at Jacksonville Jaguars, Week 6

9:30 AM · EverBank Stadium · NFL Network

Sun, Oct 18

Los Angeles Chargers at Kansas City Chiefs, Week 6

4:25 PM · Arrowhead Stadium · CBS

Sun, Oct 18

Buffalo Bills at Las Vegas Raiders, Week 6

4:25 PM · Allegiant Stadium · CBS

Sun, Oct 18

Arizona Cardinals at Los Angeles Rams, Week 6

4:05 PM · SoFi Stadium · Fox

Sun, Oct 18

New York Jets at New England Patriots, Week 6

1:00 PM · Gillette Stadium · CBS

Sun, Oct 18

New York Giants at New Orleans Saints, Week 6

1:00 PM · Caesars Superdome · Fox

Sun, Oct 18

Carolina Panthers at Philadelphia Eagles, Week 6

1:00 PM · Lincoln Financial Field · CBS

Sun, Oct 18

Tampa Bay Buccaneers at Pittsburgh Steelers, Week 6

1:00 PM · Acrisure Stadium · CBS

Mon, Oct 19

Washington Commanders at San Francisco 49ers, Week 6

8:15 PM · Levis Stadium · ESPN

▼ Week 7 14 games

Thu, Oct 22

New England Patriots at Chicago Bears, Week 7

8:15 PM · Soldier Field · Prime Video

Sun, Oct 25

Denver Broncos at Arizona Cardinals, Week 7

4:05 PM · State Farm Stadium · CBS

Sun, Oct 25

San Francisco 49ers at Atlanta Falcons, Week 7

1:00 PM · Mercedes Benz Stadium · Fox

Sun, Oct 25

Cincinnati Bengals at Baltimore Ravens, Week 7

1:00 PM · M And T Bank Stadium · CBS

Sun, Oct 25

Tampa Bay Buccaneers at Carolina Panthers, Week 7

1:00 PM · Bank Of America Stadium · Fox

Sun, Oct 25

Tennessee Titans at Cleveland Browns, Week 7

1:00 PM · Huntington Bank Field · CBS

Sun, Oct 25

Green Bay Packers at Detroit Lions, Week 7

4:25 PM · Ford Field · Fox

Sun, Oct 25

New York Giants at Houston Texans, Week 7

1:00 PM · NRG Stadium · Fox

Sun, Oct 25

Los Angeles Rams at Las Vegas Raiders, Week 7

4:25 PM · Allegiant Stadium · Fox

Sun, Oct 25

Indianapolis Colts at Minnesota Vikings, Week 7

1:00 PM · U.S. Bank Stadium · CBS

Sun, Oct 25

Miami Dolphins at New York Jets, Week 7

1:00 PM · MetLife Stadium · CBS

Sun, Oct 25

New Orleans Saints at Pittsburgh Steelers, Week 7

9:30 AM · Acrisure Stadium · NFL Network

Sun, Oct 25

Kansas City Chiefs at Seattle Seahawks, Week 7

8:20 PM · Lumen Field · NBC

Mon, Oct 26

Dallas Cowboys at Philadelphia Eagles, Week 7

8:15 PM · Lincoln Financial Field · ESPN

▼ Week 8 14 games

Thu, Oct 29

Carolina Panthers at Green Bay Packers, Week 8

8:15 PM · Lambeau Field · Prime Video

Sun, Nov 1

Baltimore Ravens at Buffalo Bills, Week 8

1:00 PM · Highmark Stadium · CBS

Sun, Nov 1

Tennessee Titans at Cincinnati Bengals, Week 8

1:00 PM · Paycor Stadium · CBS

Sun, Nov 1

Pittsburgh Steelers at Cleveland Browns, Week 8

1:00 PM · Huntington Bank Field · CBS

Sun, Nov 1

Arizona Cardinals at Dallas Cowboys, Week 8

1:00 PM · At And T Stadium · Fox

Sun, Nov 1

Kansas City Chiefs at Denver Broncos, Week 8

4:25 PM · Empower Field at Mile High · CBS

Sun, Nov 1

Minnesota Vikings at Detroit Lions, Week 8

1:00 PM · Ford Field · Fox

Sun, Nov 1

Indianapolis Colts at Jacksonville Jaguars, Week 8

1:00 PM · EverBank Stadium · CBS

Sun, Nov 1

Los Angeles Chargers at Los Angeles Rams, Week 8

4:05 PM · SoFi Stadium · Fox

Sun, Nov 1

New England Patriots at Miami Dolphins, Week 8

4:25 PM · Hard Rock Stadium · CBS

Sun, Nov 1

Las Vegas Raiders at New York Jets, Week 8

1:00 PM · MetLife Stadium · Fox

Sun, Nov 1

Atlanta Falcons at Tampa Bay Buccaneers, Week 8

1:00 PM · Raymond James Stadium · Fox

Sun, Nov 1

Philadelphia Eagles at Washington Commanders, Week 8

8:20 PM · Northwest Stadium · NBC

Mon, Nov 2

Chicago Bears at Seattle Seahawks, Week 8

8:15 PM · Lumen Field · ESPN

▼ Week 9 15 games

Thu, Nov 5

Jacksonville Jaguars at Baltimore Ravens, Week 9

8:15 PM · M And T Bank Stadium · Prime Video

Sun, Nov 8

Cincinnati Bengals at Atlanta Falcons, Week 9

9:30 AM · Mercedes Benz Stadium · NFL Network

Sun, Nov 8

Denver Broncos at Carolina Panthers, Week 9

1:00 PM · Bank Of America Stadium · CBS

Sun, Nov 8

Tampa Bay Buccaneers at Chicago Bears, Week 9

8:20 PM · Soldier Field · NBC

Sun, Nov 8

New Orleans Saints at Cleveland Browns, Week 9

1:00 PM · Huntington Bank Field · CBS

Sun, Nov 8

Dallas Cowboys at Indianapolis Colts, Week 9

1:00 PM · Lucas Oil Stadium · Fox

Sun, Nov 8

New York Jets at Kansas City Chiefs, Week 9

1:00 PM · Arrowhead Stadium · CBS / Fox

Sun, Nov 8

Houston Texans at Los Angeles Chargers, Week 9

4:05 PM · SoFi Stadium · CBS

Sun, Nov 8

Detroit Lions at Miami Dolphins, Week 9

1:00 PM · Hard Rock Stadium · Fox

Sun, Nov 8

Green Bay Packers at New England Patriots, Week 9

4:25 PM · Gillette Stadium · Fox

Sun, Nov 8

New York Giants at Philadelphia Eagles, Week 9

1:00 PM · Lincoln Financial Field · Fox

Sun, Nov 8

Las Vegas Raiders at San Francisco 49ers, Week 9

4:05 PM · Levis Stadium · CBS

Sun, Nov 8

Arizona Cardinals at Seattle Seahawks, Week 9

4:25 PM · Lumen Field · Fox

Sun, Nov 8

Los Angeles Rams at Washington Commanders, Week 9

1:00 PM · Northwest Stadium · Fox

Mon, Nov 9

Buffalo Bills at Minnesota Vikings, Week 9

8:15 PM · U.S. Bank Stadium · ESPN

▼ Week 10 14 games

Thu, Nov 12

Washington Commanders at New York Giants, Week 10

8:20 PM · MetLife Stadium · Prime Video

Sun, Nov 15

Los Angeles Rams at Arizona Cardinals, Week 10

4:05 PM · State Farm Stadium · CBS

Sun, Nov 15

Kansas City Chiefs at Atlanta Falcons, Week 10

1:00 PM · Mercedes Benz Stadium · CBS

Sun, Nov 15

Pittsburgh Steelers at Cincinnati Bengals, Week 10

8:20 PM · Paycor Stadium · NBC

Sun, Nov 15

Houston Texans at Cleveland Browns, Week 10

1:00 PM · Huntington Bank Field · Fox

Sun, Nov 15

San Francisco 49ers at Dallas Cowboys, Week 10

4:25 PM · At And T Stadium · Fox

Sun, Nov 15

New England Patriots at Detroit Lions, Week 10

9:30 AM · Ford Field · Fox

Sun, Nov 15

Minnesota Vikings at Green Bay Packers, Week 10

1:00 PM · Lambeau Field · Fox

Sun, Nov 15

Miami Dolphins at Indianapolis Colts, Week 10

1:00 PM · Lucas Oil Stadium · CBS

Sun, Nov 15

Tennessee Titans at Jacksonville Jaguars, Week 10

1:00 PM · EverBank Stadium · Fox

Sun, Nov 15

Seattle Seahawks at Las Vegas Raiders, Week 10

4:05 PM · Allegiant Stadium · CBS

Sun, Nov 15

Carolina Panthers at New Orleans Saints, Week 10

1:00 PM · Caesars Superdome · Fox

Sun, Nov 15

Buffalo Bills at New York Jets, Week 10

1:00 PM · MetLife Stadium · CBS / Fox

Mon, Nov 16

Los Angeles Chargers at Baltimore Ravens, Week 10

8:15 PM · M And T Bank Stadium · ESPN

▼ Week 11 13 games

Thu, Nov 19

Indianapolis Colts at Houston Texans, Week 11

8:15 PM · NRG Stadium · Prime Video

Sun, Nov 22

Miami Dolphins at Buffalo Bills, Week 11

1:00 PM · Highmark Stadium · Fox

Sun, Nov 22

Baltimore Ravens at Carolina Panthers, Week 11

1:00 PM · Bank Of America Stadium · Fox

Sun, Nov 22

New Orleans Saints at Chicago Bears, Week 11

1:00 PM · Soldier Field · Fox

Sun, Nov 22

Tennessee Titans at Dallas Cowboys, Week 11

1:00 PM · At And T Stadium · Fox

Sun, Nov 22

Las Vegas Raiders at Denver Broncos, Week 11

4:25 PM · Empower Field at Mile High · CBS

Sun, Nov 22

Tampa Bay Buccaneers at Detroit Lions, Week 11

1:00 PM · Ford Field · CBS

Sun, Nov 22

Arizona Cardinals at Kansas City Chiefs, Week 11

1:00 PM · Arrowhead Stadium · CBS

Sun, Nov 22

New York Jets at Los Angeles Chargers, Week 11

4:05 PM · SoFi Stadium · Fox

Sun, Nov 22

San Francisco 49ers at Minnesota Vikings, Week 11

8:20 PM · U.S. Bank Stadium · NBC

Sun, Nov 22

Jacksonville Jaguars at New York Giants, Week 11

1:00 PM · MetLife Stadium · CBS

Sun, Nov 22

Pittsburgh Steelers at Philadelphia Eagles, Week 11

4:25 PM · Lincoln Financial Field · CBS

Mon, Nov 23

Cincinnati Bengals at Washington Commanders, Week 11

8:15 PM · Northwest Stadium · ESPN

▼ Week 12 16 games

Wed, Nov 25

Green Bay Packers at Los Angeles Rams, Week 12

10:00 PM · SoFi Stadium · Netflix

Thu, Nov 26

Kansas City Chiefs at Buffalo Bills, Week 12

8:20 PM · Highmark Stadium · NBC

Thu, Nov 26

Philadelphia Eagles at Dallas Cowboys, Week 12

4:30 PM · At And T Stadium · Fox

Thu, Nov 26

Chicago Bears at Detroit Lions, Week 12

1:00 PM · Ford Field · CBS

Fri, Nov 27

Denver Broncos at Pittsburgh Steelers, Week 12

3:00 PM · Acrisure Stadium · Prime Video

Sun, Nov 29

Washington Commanders at Arizona Cardinals, Week 12

4:25 PM · State Farm Stadium · Fox

Sun, Nov 29

Houston Texans at Baltimore Ravens, Week 12

1:00 PM · M And T Bank Stadium · CBS

Sun, Nov 29

New Orleans Saints at Cincinnati Bengals, Week 12

1:00 PM · Paycor Stadium · CBS

Sun, Nov 29

Las Vegas Raiders at Cleveland Browns, Week 12

1:00 PM · Huntington Bank Field · Fox

Sun, Nov 29

New York Giants at Indianapolis Colts, Week 12

1:00 PM · Lucas Oil Stadium · Fox

Sun, Nov 29

Tennessee Titans at Jacksonville Jaguars, Week 12

4:05 PM · EverBank Stadium · CBS / Fox

Sun, Nov 29

New England Patriots at Los Angeles Chargers, Week 12

8:20 PM · SoFi Stadium · NBC

Sun, Nov 29

New York Jets at Miami Dolphins, Week 12

1:00 PM · Hard Rock Stadium · CBS

Sun, Nov 29

Atlanta Falcons at Minnesota Vikings, Week 12

1:00 PM · U.S. Bank Stadium · Fox

Sun, Nov 29

Seattle Seahawks at San Francisco 49ers, Week 12

4:25 PM · Levis Stadium · Fox

Mon, Nov 30

Carolina Panthers at Tampa Bay Buccaneers, Week 12

8:15 PM · Raymond James Stadium · ESPN

▼ Week 13 14 games

Thu, Dec 3

Kansas City Chiefs at Los Angeles Rams, Week 13

8:15 PM · SoFi Stadium · Amazon / Prime Video

Sun, Dec 6

Philadelphia Eagles at Arizona Cardinals, Week 13

4:05 PM · State Farm Stadium · Fox

Sun, Dec 6

Detroit Lions at Atlanta Falcons, Week 13

1:00 PM · Mercedes Benz Stadium · CBS

Sun, Dec 6

Jacksonville Jaguars at Chicago Bears, Week 13

1:00 PM · Soldier Field · Fox

Sun, Dec 6

Cincinnati Bengals at Cleveland Browns, Week 13

1:00 PM · Huntington Bank Field · CBS

Sun, Dec 6

Miami Dolphins at Denver Broncos, Week 13

4:05 PM · Empower Field at Mile High · Fox

Sun, Dec 6

Pittsburgh Steelers at Houston Texans, Week 13

8:20 PM · NRG Stadium · NBC

Sun, Dec 6

Tampa Bay Buccaneers at Los Angeles Chargers, Week 13

1:00 PM · SoFi Stadium · CBS

Sun, Dec 6

Carolina Panthers at Minnesota Vikings, Week 13

4:25 PM · U.S. Bank Stadium · CBS

Sun, Dec 6

Buffalo Bills at New England Patriots, Week 13

4:25 PM · Gillette Stadium · CBS

Sun, Dec 6

Green Bay Packers at New Orleans Saints, Week 13

1:00 PM · Caesars Superdome · Fox

Sun, Dec 6

San Francisco 49ers at New York Giants, Week 13

1:00 PM · MetLife Stadium · Fox

Sun, Dec 6

Washington Commanders at Tennessee Titans, Week 13

1:00 PM · Nissan Stadium · CBS

Mon, Dec 7

Dallas Cowboys at Seattle Seahawks, Week 13

8:15 PM · Lumen Field · ESPN

▼ Week 14 15 games

Thu, Dec 10

Minnesota Vikings at New England Patriots, Week 14

8:15 PM · Gillette Stadium · Prime Video

Sun, Dec 13

Tampa Bay Buccaneers at Baltimore Ravens, Week 14

1:00 PM · M And T Bank Stadium · Fox

Sun, Dec 13

New Orleans Saints at Carolina Panthers, Week 14

1:00 PM · Bank Of America Stadium · CBS

Sun, Dec 13

Kansas City Chiefs at Cincinnati Bengals, Week 14

4:25 PM · Paycor Stadium · Fox

Sun, Dec 13

Atlanta Falcons at Cleveland Browns, Week 14

1:00 PM · Huntington Bank Field · CBS

Sun, Dec 13

Tennessee Titans at Detroit Lions, Week 14

1:00 PM · Ford Field · Fox

Sun, Dec 13

Buffalo Bills at Green Bay Packers, Week 14

8:20 PM · Lambeau Field · NBC

Sun, Dec 13

Washington Commanders at Houston Texans, Week 14

1:00 PM · NRG Stadium · CBS

Sun, Dec 13

Los Angeles Chargers at Las Vegas Raiders, Week 14

4:05 PM · Allegiant Stadium · CBS

Sun, Dec 13

San Francisco 49ers at Los Angeles Rams, Week 14

4:25 PM · SoFi Stadium · Fox

Sun, Dec 13

Chicago Bears at Miami Dolphins, Week 14

1:00 PM · Hard Rock Stadium · CBS / Fox

Sun, Dec 13

Denver Broncos at New York Jets, Week 14

1:00 PM · MetLife Stadium · CBS

Sun, Dec 13

Indianapolis Colts at Philadelphia Eagles, Week 14

1:00 PM · Lincoln Financial Field · Fox

Sun, Dec 13

New York Giants at Seattle Seahawks, Week 14

4:25 PM · Lumen Field · Fox

Mon, Dec 14

Pittsburgh Steelers at Jacksonville Jaguars, Week 14

8:15 PM · EverBank Stadium · ESPN

▼ Week 15 16 games

Thu, Dec 17

San Francisco 49ers at Los Angeles Chargers, Week 15

8:15 PM · SoFi Stadium · Prime Video

Sat, Dec 19

Chicago Bears at Buffalo Bills, Week 15

8:20 PM · Highmark Stadium · CBS

Sat, Dec 19

Seattle Seahawks at Philadelphia Eagles, Week 15

5:00 PM · Lincoln Financial Field · Fox

Sun, Dec 20

New York Jets at Arizona Cardinals, Week 15

4:05 PM · State Farm Stadium · Fox

Sun, Dec 20

Cincinnati Bengals at Carolina Panthers, Week 15

1:00 PM · Bank Of America Stadium · Fox

Sun, Dec 20

Las Vegas Raiders at Denver Broncos, Week 15

4:25 PM · Empower Field at Mile High · CBS

Sun, Dec 20

Miami Dolphins at Green Bay Packers, Week 15

1:00 PM · Lambeau Field · Fox

Sun, Dec 20

Jacksonville Jaguars at Houston Texans, Week 15

1:00 PM · NRG Stadium · CBS

Sun, Dec 20

Tennessee Titans at Indianapolis Colts, Week 15

1:00 PM · Lucas Oil Stadium · CBS

Sun, Dec 20

Dallas Cowboys at Los Angeles Rams, Week 15

4:25 PM · SoFi Stadium · CBS

Sun, Dec 20

Detroit Lions at Minnesota Vikings, Week 15

8:20 PM · U.S. Bank Stadium · NBC

Sun, Dec 20

Cleveland Browns at New York Giants, Week 15

1:00 PM · MetLife Stadium · CBS

Sun, Dec 20

Baltimore Ravens at Pittsburgh Steelers, Week 15

1:00 PM · Acrisure Stadium · CBS

Sun, Dec 20

New Orleans Saints at Tampa Bay Buccaneers, Week 15

1:00 PM · Raymond James Stadium · Fox

Sun, Dec 20

Atlanta Falcons at Washington Commanders, Week 15

1:00 PM · Northwest Stadium · CBS / Fox

Mon, Dec 21

New England Patriots at Kansas City Chiefs, Week 15

8:15 PM · Arrowhead Stadium · ESPN

▼ Week 16 16 games

Thu, Dec 24

Houston Texans at Philadelphia Eagles, Week 16

8:15 PM · Lincoln Financial Field · Prime Video

Fri, Dec 25

Denver Broncos at Buffalo Bills, Week 16

4:30 PM · Highmark Stadium · NFL Network / Netflix

Fri, Dec 25

Green Bay Packers at Chicago Bears, Week 16

1:00 PM · Soldier Field · Netflix

Fri, Dec 25

Los Angeles Rams at Seattle Seahawks, Week 16

8:15 PM · Lumen Field · Fox

Sat, Dec 26

Washington Commanders at Minnesota Vikings, Week 16

TBD · U.S. Bank Stadium · TBD

Sun, Dec 27

Cleveland Browns at Baltimore Ravens, Week 16

1:00 PM · M And T Bank Stadium · CBS

Sun, Dec 27

Jacksonville Jaguars at Dallas Cowboys, Week 16

8:20 PM · At And T Stadium · NBC

Sun, Dec 27

San Francisco 49ers at Kansas City Chiefs, Week 16

4:25 PM · Arrowhead Stadium · CBS

Sun, Dec 27

Tennessee Titans at Las Vegas Raiders, Week 16

4:05 PM · Allegiant Stadium · Fox

Sun, Dec 27

Los Angeles Chargers at Miami Dolphins, Week 16

1:00 PM · Hard Rock Stadium · Fox

Sun, Dec 27

Arizona Cardinals at New Orleans Saints, Week 16

1:00 PM · Caesars Superdome · Fox

Sun, Dec 27

New England Patriots at New York Jets, Week 16

1:00 PM · MetLife Stadium · CBS

Mon, Dec 28

New York Giants at Detroit Lions, Week 16

8:15 PM · Ford Field · ESPN

Sun, Dec 27

Tampa Bay Buccaneers at Atlanta Falcons, Week 16

TBD · Mercedes Benz Stadium · TBD

Sun, Dec 27

Pittsburgh Steelers at Carolina Panthers, Week 16

TBD · Bank Of America Stadium · TBD

Sun, Dec 27

Cincinnati Bengals at Indianapolis Colts, Week 16

TBD · Lucas Oil Stadium · TBD

▼ Week 17 16 games

Thu, Dec 31

Baltimore Ravens at Cincinnati Bengals, Week 17

8:15 PM · Paycor Stadium · Prime Video

Sun, Jan 3

Washington Commanders at Jacksonville Jaguars, Week 17

TBD · EverBank Stadium · TBD

Sun, Jan 3

Las Vegas Raiders at Arizona Cardinals, Week 17

4:05 PM · State Farm Stadium · CBS

Sun, Jan 3

New Orleans Saints at Atlanta Falcons, Week 17

1:00 PM · Mercedes Benz Stadium · Fox

Sun, Jan 3

Seattle Seahawks at Carolina Panthers, Week 17

1:00 PM · Bank Of America Stadium · Fox

Sun, Jan 3

Detroit Lions at Chicago Bears, Week 17

4:25 PM · Soldier Field · Fox

Sun, Jan 3

Indianapolis Colts at Cleveland Browns, Week 17

1:00 PM · Huntington Bank Field · Fox

Sun, Jan 3

New York Giants at Dallas Cowboys, Week 17

1:00 PM · At And T Stadium · Fox

Sun, Jan 3

Buffalo Bills at Miami Dolphins, Week 17

1:00 PM · Hard Rock Stadium · CBS

Sun, Jan 3

Minnesota Vikings at New York Jets, Week 17

1:00 PM · MetLife Stadium · CBS

Sun, Jan 3

Tennessee Titans at Pittsburgh Steelers, Week 17

1:00 PM · Acrisure Stadium · CBS

Sun, Jan 3

Philadelphia Eagles at San Francisco 49ers, Week 17

8:20 PM · Levis Stadium · NBC

Sun, Jan 3

Los Angeles Rams at Tampa Bay Buccaneers, Week 17

TBD · Raymond James Stadium · TBD

Mon, Jan 4

Houston Texans at Green Bay Packers, Week 17

8:15 PM · Lambeau Field · ESPN

Sun, Jan 3

Kansas City Chiefs at Los Angeles Chargers, Week 17

TBD · SoFi Stadium · TBD

Sun, Jan 3

Denver Broncos at New England Patriots, Week 17

TBD · Gillette Stadium · TBD

▼ Week 18 16 games

Sun, Jan 10

Philadelphia Eagles at New York Giants, Week 18

TBD · MetLife Stadium · TBD

Sun, Jan 10

San Francisco 49ers at Arizona Cardinals, Week 18

TBD · State Farm Stadium · TBD

Sun, Jan 10

Pittsburgh Steelers at Baltimore Ravens, Week 18

TBD · M And T Bank Stadium · TBD

Sun, Jan 10

New York Jets at Buffalo Bills, Week 18

TBD · Highmark Stadium · TBD

Sun, Jan 10

Atlanta Falcons at Carolina Panthers, Week 18

TBD · Bank Of America Stadium · TBD

Sun, Jan 10

Cleveland Browns at Cincinnati Bengals, Week 18

TBD · Paycor Stadium · TBD

Sun, Jan 10

Washington Commanders at Dallas Cowboys, Week 18

TBD · At And T Stadium · TBD

Sun, Jan 10

Los Angeles Chargers at Denver Broncos, Week 18

TBD · Empower Field at Mile High · TBD

Sun, Jan 10

Detroit Lions at Green Bay Packers, Week 18

TBD · Lambeau Field · TBD

Sun, Jan 10

Tennessee Titans at Houston Texans, Week 18

TBD · NRG Stadium · TBD

Sun, Jan 10

Jacksonville Jaguars at Indianapolis Colts, Week 18

TBD · Lucas Oil Stadium · TBD

Sun, Jan 10

Las Vegas Raiders at Kansas City Chiefs, Week 18

TBD · Arrowhead Stadium · TBD

Sun, Jan 10

Seattle Seahawks at Los Angeles Rams, Week 18

TBD · SoFi Stadium · TBD

Sun, Jan 10

Chicago Bears at Minnesota Vikings, Week 18

TBD · U.S. Bank Stadium · TBD

Sun, Jan 10

Miami Dolphins at New England Patriots, Week 18

TBD · Gillette Stadium · TBD

Sun, Jan 10

Tampa Bay Buccaneers at New Orleans Saints, Week 18

TBD · Caesars Superdome · TBD

Los Angeles Chargers vs San Francisco 49ers Odds, Top Picks & Predictions

San Francisco 49ers